PRE-CONFERENCE WORKSHOP DAY I MARCH 25, 2025
12:30 pm Check-In & Refreshments
1:00pm Workshop
Delving into the Emerging Technological Advancements & Techniques For Characterizing Drugs for a More Holistic Approach to Discovery
Synopsis
Advance Your Drug Discovery with Cutting-Edge Biophysics: This workshop offers a focused exploration of essential biophysical techniques, from SPR and HTS to advanced methods like DELs and MST, and emerging areas like covalent modalities. Learn how to leverage these tools for efficient hit identification, detailed interaction analysis, and optimised lead development. Gain practical insights from expert-led sessions on computational methods, NMR, and single-molecule approaches. Explore real-world applications through in-depth case studies demonstrating biophysics across the drug discovery pipeline. Discover how to apply these strategies across the drug discovery pipeline and accelerate your research.
- Discovering a Comprehensive Biophysical Toolkit through a wide range of biophysical techniques, from HTS and FBDD to advanced methods like SPR, ASMS, DELs, nanoDSF, MST, NMR, and single-molecule techniques, showcasing their application across the drug discovery pipeline
- Investigating Case Studies using three detailed projects to demonstrate the practical application of biophysics in stabilising unstable proteins, identifying hits against challenging targets, and elucidating mechanisms of action for therapeutic molecules
- Exploring Structure-Function Relationships by emphasizes the importance of understanding drug-target interactions, including kinetic parameters, binding affinities, and structural insights, with a focus on how these insights drive lead optimisation
- Uncovering Innovation and Emerging Modalities by addressing cutting-edge developments in biophysics, including the use of computational approaches and the growing importance of covalent modalities in drug design