EDT: Electron Density Topography, An Orthogonal Technique to Observe 3D Information in Solution
- Introduction to our novel technique that enables the observation of molecular complexes in solution overnight, with no need for labeling and molecular information in principle
- Presentation of our POC examples on low-resolution direct epitope mapping, geospecific semi-quantitation of ADC payload introduction, and virus capsid observation with nucleotide content that might lead to absolute quantification of P/N ratio
- Other cases on visualizing the binding area of peptide ligands, oligomer formation of small proteins, and tracking the denaturation-refolding process
- Other characteristics assessments related to developabilities