Leveraging Biophysical Tools to Accelerate RSV Vaccine Development: From Structural Insight to Functional Efficacy

  • Establishing the structure and conformational integrity of RSV protein antigens and linking structural state to immunogenicity 
  • Applying biophysical tools to characterise stability, aggregation, and conformational dynamics to optimise vaccine candidates early
  • Using orthogonal biophysical methods to guide candidate selection, improve manufacturability, and reduce late-stage failure risk