Leveraging Biophysics for Efficient and Effective DNA Encoded Library Screening
Time: 8:30 am
day: Conference Day One
Details:
- Delve into the unique benefits and challenges associated with utilizing DNA-encoded libraries for high-throughput hit identification
- Explore the integration of advanced biophysical techniques such as with cryo-EM, thermal shift assays (nanoDSF), fluorescence-based proximity assays (trFRET, alphaLISA) in screening large libraries for meaningful interactions
- Strategies for enhancing the efficiency and accuracy of hit discovery