Leveraging Structure-Driven Molecular Design with Tuneable Functional Properties for a Hybrid Biophysics-Centric Framework
- Explore the design and triage of proteins with customised and biased functional properties using structure-guided molecular design and iterative design–test–qualify cycles to accelerate early engineering decisions
- Integrate biochemical and biophysical techniques to validate structural hypotheses, ensure reagent fitness, and uncover mechanistic insights through emerging hybrid biophysics approaches
- Deploy a holistic, modality-agnostic biophysics strategy across soluble and membrane proteins, multi-target systems, and diverse modalities to de-risk hit validation and drive high-confidence early discovery