Navigating the Unique Biophysical Profiling Challenges of Membrane Associated Targets During Optimization
Time: 2:30 pm
day: Conference Day One
Details:
- Exploring the unique challenges of characterizing membrane proteins when isolated from natural membrane environment including expression, purification, and stability
- Exploring negative stain and differential scanning fluorimetry in providing insights into protein stability and conformational flexibility and other innovative techniques tailored for membrane proteins
- Leveraging structural studies of membrane-associated targets to inform and guide lead optimization strategies
