Goran Malojcic
Company: Novartis AG
Job title: Group Leader, Biochemistry & Biophysics
Seminars:
Fragment-Based Discovery of Reveals Unprecedented Ligandability and Enables Direct Targeting of a Cancer-Relevant Transcription Factor 12:45 pm
Transcription factors remain of high interest in oncology and other disease areas Direct targeting of certain classes or domains of transcription factors is unexplored, and they are considered undruggable Fragment screening and optimization, driven by multiple orthogonal biophysical techniques coupled with structure-based design, enabled the discovery of ligands targeting such a transcription factorRead more
day: Day 2